The purpose of our study is to use a flaxseed-based nutritional supplement in combination with exercise training (walking) for improving cholesterol levels. We hypothesize that exercise training will improve cholesterol profile and that adding supplementation with a flaxseed nutritional supplement will further improve cholesterol profile.
Flax supplementation and exercise training each have small beneficial effects for improving blood lipid profile and reducing cardiovascular disease risk. Flax lignan, a phytoestrogen found in flaxseed is thought to be the active compound responsible for the cholesterol-lowering effect of flaxseed. Our purpose is to combine an exercise training program (walking) with flax lignan supplementation for improving blood lipid profile. Comparisons: Walking (6 days per week) plus flax lignan (500 mg per day) compared to walking plus placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
100
543 mg SDG per day
walking 45 minutes per day 5 days per week
University of Saskatchewan
Saskatoon, Saskatchewan, Canada
metabolic syndrome score
Time frame: 6 months
Total cholesterol at 2, 4, and 6 months
Time frame: 6 months
High density lipoprotein at 2, 4, and 6 months
Time frame: 6 months
Low density lipoprotein at 2, 4, and 6 months
Time frame: 6 months
Triglycerides at 2, 4, and 6 months
Time frame: 6 months
Blood glucose at 2, 4, and 6 months
Time frame: 6 months
Body composition at 6 months
Time frame: 6 months
Aerobic fitness at 6 months
Time frame: 6 months
Waist Girth at 6 months
Time frame: 6 months
Body mass index at 6 months
Time frame: 6 months
Lumbar spine bone mineral density at 6 months
Time frame: 6 months
Proximal femur bone mineral density at 6 months
Time frame: 6 months
Whole body bone mineral density at 6 months
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Time frame: 6 months
Trunk fat skinfolds at 6 months
Time frame: 6 months
inflammatory cytokines
Time frame: 6 months