Iodixanol in Multidetector-Row Computed Tomography-Coronary Angiography (MDCT-CA)

Phase 4CompletedNCT00209404

GE Healthcare50 enrolled

Overview

Image quality in coronary artery computed tomography is influenced by the heart rate variation during the examination. The purpose of this clinical trial is to investigate the change in heart rate following injection of a contrast medium called Visipaque™ (iodixanol). Image quality and diagnostic quality of the examination will be evaluated.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Coronary Artery Disease

Interventions

Iodixanol 320 mg I/MlDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects with low to moderate suspicion of coronary artery disease referred for retrospective electrocardiogram (ECG)-gated multidetector row computed tomography coronary angiography and with a heart rate \>75 beats per minute (bpm) will be included. Exclusion Criteria: * Subjects who take medications that slow down the heart rate or present cardiac arrhythmia at rest will not be included.

Locations (1)

Amersham Health S.A.

Vélizy-Villacoublay, France

Outcomes

Primary Outcomes

Change in mean heart rate

Secondary Outcomes

Image quality

Diagnostic quality

Overall diagnostic information

Frequency and intensity of adverse events

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.