Efficacy Study of Dysport® in the Treatment of Anal Fissure.

Inclusion Criteria: * Patients having idiopathic anal fissure in the posterior anal midline * Patients having anal fissure present for less than 6 months * Patients having symptoms (pain) present for a minimum of 2 weeks and not responding after 2 weeks of standard therapy (diet, laxatives, sitz-bathes) Exclusion Criteria: * Patients having anal fistulas or anal fissure of various causes such as Crohn disease, Behcet infectious ulceration, anal suppuration, subfissural infiltration, abscesses, acute haemorrhoidal attacks or inflammatory bowel disease * Patients having idiopathic anal fissure in the anterior anal midline * Patients having lateral or multiple fissures * Patients having anal or perianal cancer * Patients who underwent previous anal surgery or have cicatricial alterations or post-surgical cicatricial lesions * Patients receiving drugs affecting neuromuscular transmission * Patients who have received topical anaesthetic within 3 days of injection * Patients receiving local treatment by myorelaxing agent * Patients receiving prohibited analgesics * Patients having bleeding disturbances or currently using coumarin derivates * Patients having myasthenia or any genetic muscle disease