Tuberculosis Research Blood Bank

N/AWithdrawnNCT00212498

NYU Langone Health

Overview

To create a Tuberculosis Research Blood Bank for future molecular genetics and serological studies

Study Type

OBSERVATIONAL

Conditions

Tuberculosis

Interventions

Develop a bank of blood samples from patients infected with TB for future molecular genetics studies and serological studiesPROCEDURE

Blood sample

Eligibility

Sex: ALLMin age: 21 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * TB suspect with positive sputum smear

Locations (1)

NYU School of Medicine Division of Pulmonary and Critical Care Medicine

New York, New York, United States

Outcomes

Primary Outcomes

Develop TB Blood Bank

To develop a bank of blood samples (serum, plasma, buffy coat DNA) and urine from patients infected with TB. This blood and urine will be used for future molecular genetics studies. Demographic data will be collected and samples will be stored by number. The banked specimens will be evaluated in an attempt to identify susceptibility genes in TB disease. Specifically, expression of the human Bcg gene that codes for resistance to M. tuberculosis will be evaluated and its expression correlated expression with gender, race, clinical TB characteristics. Each patient will have a unique identifier and therefore data generated from this analysis will not be linkable to the patient.

Time frame: Long-Term

Data from ClinicalTrials.gov

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