Cerebral Resonance Magnetic Imaging During Rectal Distention

University Hospital, Rouen

Overview

Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown. The purpose of this study is to look for a different cerebral response by magnetic resonance imaging after rectal stimulation in patients with irritable bowel syndrome compared to healthy subjects and to patients with digestive organic disease. Our hypothesis is that irritable bowel syndrome could be a problem of cerebral integration of visceral stimulation.

Study Type

OBSERVATIONAL

Conditions

Ulcerative Colitis Irritable Bowel Syndrome

Interventions

rectal distensionPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy subjects irritable bowel syndrome (Rome II criteria) colitis ulcerative Exclusion Criteria: pregnant or breast feeding metallic material implanted good tolerance of rectal distension acute phase of ulcerative colitis

Locations (1)

University hospital of Rouen

Rouen, France

Data from ClinicalTrials.gov

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