Hand and foot skin diseases, such as dermatitis and psoriasis, that do not respond to topical creams can be treated with ultraviolet light therapy. Topical psoralen plus ultraviolet A (PUVA) is commonly used to treat these conditions, but requires additional time for the hands and feet to soak in psoralens before the light treatment. Newer narrowband ultraviolet B (NBUVB) units have become available which allow for light treatment without soaking first. The purpose of this study is to determine if NBUVB is as effective as PUVA for hand and foot skin diseases.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
3
Mayo Clinic
Rochester, Minnesota, United States
Number of treatments required to reach clearance
Time frame: Baseline to 15 months
Change in symptom score (erythema, scaling/hyperkeratosis, papular/vesicular eruption, and fissures)
Time frame: Baseline to 15 months
Change in global score
Time frame: Baseline to 15 months
Number of patients reaching clearance
Time frame: Baseline to 15 months
Adverse effects
Time frame: Baseline to 15 months
Number of days in remission
Time frame: Baseline to 15 months
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