Glutamine in Preventing Myalgia and/or Arthralgia in Patients Who Are Receiving Paclitaxel For Cancer

Inclusion Criteria. * Signed informed patient consent * Adult patients (Age \> 18 years old) with a neoplastic disorder requiring paclitaxel as part of therapy, whether curative or palliative intent. * Patients must have \> 2 additional planned courses of paclitaxel. * Patients may be out-patient or in-patient at the time of enrollment. * Patient must have had myalgias and/or arthralgias with the most recent course(s) of paclitaxel. Paclitaxel must be being administered over 3 hours or less for each infusion. * Patients may have chronic pain but they must be able to differentiate it from either myalgias or arthralgias and be on a stable medication regimen for pain management. * Eastern Cooperative Group (ECOG) Performance status score \< 3 * If consenting for the laboratory portion of the study the participant must have normal creatinine phosphokinase within 14 days of study entry. * The patient, if sexually active, must be willing to agree to use an approved form of birth control. Exclusion criteria. * The patient has received another investigational drug within the past 30 days. * No myalgias or arthralgias in prior paclitaxel courses. * The patient has uncontrolled (over the last 30 days), clinically significant confounding medical conditions such as rheumatoid disease, fibromyalgia, or chronic fatigue syndrome. Also if the patient has a viral infection, cold symptoms, fever (\> 38 C -degrees celsius) or influenza. * Patients with existing neuropathies or neurologic disorders which would prevent them from accurately assessing the onset or extent of myalgias and arthralgias. * The patient has had significant medical intervention in the last 30 days * The patient is pregnant or lactating. * Patients who are unable to take oral medications or with medical conditions that might inhibit their ability to absorb protein from the gastrointestinal tract. * Patients who are unwilling to abstain from additional protein supplements of any kind other than that obtained through "normal" dietary intake. * Patients required to take nonsteroidal anti-inflammatory agents (NSAIDS), antioxidant vitamins, and unable or unwilling to abstain from them for 1 week prior to and during glutamine/placebo therapy. * Patients with metabolic errors or abnormalities of protein metabolism. * Patients with a history of blood urea nitrogen level \> 2 times normal with a normal serum creatinine.