The purpose of this study is to compare the use of fluoroscopic guidance, (a commonly used X-ray technique), with the traditional approach, (where the doctors feel for the strongest pulse), to obtain access to the blood vessel in the groin. These two methods are being compared to assess which is faster, safer and more often allows your physician to use an "arterial closure device," a small suture or plug applied at the end of the angiogram where the needle enters your blood vessel if he/she chooses.
Design: A prospective, randomized, controlled clinical trial to study the effectiveness of applying fluoroscopy guided femoral artery access in the cardiac catheterization lab and its effect on the usage of FDA approved femoral artery closure devices. This trial will randomize patients between fluoroscopy guided femoral artery access or femoral artery access using the usual anatomic landmarks and will then study the difference in the ability to use closure devices on the access site. Purpose: To establish the safety and efficacy of using fluoroscopic assistance to allow access of the common femoral artery rather than its branches and thus increase the ability to use closure devices. Enrollment: An approximate enrollment of up to 1000 patients (all patients randomized) who will be undergoing cardiac catheterization and who meet all the eligibility criteria at OUMC and VAMC in Oklahoma City. Duration: The study will be conducted over approximately one year. Primary Endpoint: Prediction of ability to use femoral artery closure device based on angiographic data of the femoral artery from fluoroscopy arm versus traditional technique arm. Secondary Endpoints: 1. Compare the incidence of known major side effects of femoral artery puncture between the two methods of access 2. Compare the time and number of attempts needed to obtain arterial access between the two groups of patients. 3. Compare the ability to puncture the common femoral artery using fluoroscopy vs. anatomical landmarks among different levels of trainees (cardiology fellows) and attending cardiologists. 4. Assess whether fluoroscopic guidance is a superior method to obtain access and thus should be used as a training technique for cardiology fellows. Analytical Subset: Intention-to-treat sample
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
990
Use of fluoroscopy during arterial insertion of coronary catheter
Standard coronary angiography technique; no fluoroscopic assistance
University of Oklahoma Medical Center
Oklahoma City, Oklahoma, United States
Veterans Affairs Medical Center
Oklahoma City, Oklahoma, United States
Prediction of ability to use femoral artery closure device based on angiographic data of the femoral artery from fluoroscopy arm versus traditional technique arm.
Time frame: 24 hours
Compare the incidence of known major side effects of femoral artery puncture between the two methods of access
Time frame: 24 hours
Compare the time and number of attempts needed to obtain arterial access between the two groups of patients.
Time frame: Intraprocedural
Compare the ability to puncture the common femoral artery using fluoroscopy vs. anatomical landmarks among different levels of trainees (cardiology fellows) and attending cardiologists.
Time frame: Intraprocedural
Assess whether fluoroscopic guidance is a superior method to obtain access and thus should be used as a training technique for cardiology fellows.
Time frame: End of study analysis
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