Esomeprazole for Treatment of GERD in Pediatric Patients

Inclusion Criteria: * Patients' parents/guardians must provide written informed consent prior to the execution of any study-related procedures. * Patients who are able to comprehend their involvement in a clinical study, including risks and benefits, (typically ≥6 years of age) must have assent documented by study personnel prior to any study-related procedures. * Patients must be diagnosed with endoscopically proven GERD by the investigator during the screening period or have a previous (within 2 weeks prior to Visit 1) diagnosis of erosive esophagitis by endoscopy and are candidates for PPI therapy. Exclusion Criteria: * Patients who have used a proton pump inhibitor within 14 days prior to randomization, including over-the-counter omeprazole. * Patients who have used any prescription or over-the-counter (OTC) treatment (other than proton pump inhibitors) for symptoms of GERD, such as histamine 2 receptor antagonists or prokinetics, within 72 hours prior to randomization. * Patients with a known hypersensitivity, allergy, or intolerance to any component of esomeprazole or omeprazole.