Effect of APC and Epo on the Inflammatory Response During Sepsis

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's40 enrolled

Overview

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis.

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis. Patients already prescribed either drug will be enrolled. The microcirculation of the sublingual vascular bed will be observed with a microscope to detect the alterations in the inflammatory response.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sepsis Systemic Inflammation

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients in the ICU in severe septic shock undergoing APC and/or Epo treatment Exclusion Criteria: * any severe comorbid conditions

Locations (1)

Lawson Health Research Institute

London, Ontario, Canada

Data from ClinicalTrials.gov

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