Pimecrolimus Cream 1% in Adult Patients With Perioral Dermatitis

Inclusion Criteria: * clinically diagnosed perioral dermatitis associated or not associated with topical steroid use (the periorbital area may also be involved in addition to the perioral region) * minimum severity score (PODSI) ≥ 4 * age 18 and older Exclusion Criteria: * Ongoing use of the following treatments is NOT allowed after the start of study drug: Oral tetracyclines, oral erythromycin, oral steroids and oral calcineurin inhibitors. All topical treatments of the face, including steroids, calcineurin inhibitors, metronidazole, tetracyclines, erythromycin and emollients (exception: DAC Basiscreme). * Systemic immunosuppression * History of malignancy of any organ system, treated or untreated, within the past 5 years