Irinotecan, 5-Fluorouracil and Leucovorin With or Without Iressa in the Treatment of Metastatic Colorectal Cancer

Inclusion Criteria: * Histologically confirmed metastatic colorectal cancer * Presence of measurable metastases * No previous treatment for metastatic cancer Exclusion Criteria: * No presence of Central Nervous System metastases * No other co-existing malignancies or malignancies diagnosed within the last 5 years with the exception of basal cell carcinoma or cervical cancer in situ * Any evidence of severe or uncontrolled systemic disease (e.g. unstable or uncompensated respiratory, cardiac, hepatic or renal disease)