Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test

Technische Universität Dresden14 enrolled

Overview

The purpose of this study is to evaluate the efficacy of the topical therapies Protopic and Advantan as well as their combination against placebo in a Psoriasis Plaque Test

daily psoriasis plaque tests for two weeks and optical coherence tomography (OCT) and 20-MHz-ultrasound on day 0 and day 11, 10 days post end of treatment and 20 days post end of treatment

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Psoriasis Vulgaris

Interventions

Protopic, AdvantanDRUG

Blood and Urine TestPROCEDURE

coherence tomographyPROCEDURE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients older than 18 Years * Negative urine pregnancy test * Written informed consent * Good compliance Exclusion Criteria: * Patients less than 18 years * Pregnant patients * Patients with renal insufficiency, liver diseases * Patients who received systemic antipsoriatic treatment or UV treatment less than 4 weeks prior to study * Patients who used topical antipsoriatics within two weeks prior to study * Immunosuppressed Patients

Locations (1)

Technische Universität Dresden

Dresden, Saxony, Germany

Outcomes

Primary Outcomes

sum score of psoriasis plaque tests on day 11

Secondary Outcomes

20-MHz-ultrasound and OCT on day 11

Data from ClinicalTrials.gov

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