Dose Effects of Hormone Therapy (Two Doses of Estradiol Associated to Progesterone) on Inflammatory Markers

Inclusion Criteria: * Symptomatic menopausal women : \>=50 years and amenorrhea \>=1 year or \<50 years and amenorrhea \>=1 year and plasmatic FSH \>= 30 UI/l * Normal mammography in the last 2 years before inclusion * Normal cervical smear in the last 2 years before inclusion * Written consent for participation in the study Exclusion Criteria: * Unconfirmed Menopause with amenorrhoea of less than year * Oestrogen-progesterone Treatment anterior in 3 months previous the inclusion * Recently a viral Infection or bacteriologic(at least of 2 weeks) * Dental Infection * Inflammatory Pathology chronicles * Antecedent of pathology cancerous with or no a sly hemopathy * Addiction to smoking of more than 20 cigarettes a day or an alcoholic consumption furthermore of 4 glasses a day * Taken concomitant of one of the treatments forbidden:statine, vitamin B6 or B12, folates, antiinflammatory, anti aggregant Plaquettes, DHEA, phytoestrogens * Refusal to sign the assent informed * Not membership in a regime about social security