To evaluate the efficacy and safety of SBRT for T1N0M0 non-small cell lung cancer
To evaluate the efficacy and safety of SBRT for T1N0M0 non-small cell lung cancer,the following questions should be answered. Can SRT be an alternative standard treatment modality for inoperable patients? Can SRT can be a comparable standard treatment modality with lobectomy for operable patients? 12 Gy is the daily dose at the isocenter,and 48 Gy in total by 4 fractions will be irradiated by stereotactic irradiation over 4 to 8 days.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
167
Procedure/Surgery: stereotactic body radiation therapy
Kyushu University Hospital
Fukuoka,Higashi-ku,Maidashi,3-1-1, Fukuoka, Japan
Hiroshima University, School of Medicine
Hiroshima,Minami-ku,Kasumi,1-2-3, Hiroshima, Japan
3-years overall survival
Time frame: During the study conduct
Overall survival
Time frame: During the study conduct
relapse-free survival
Time frame: During the study conduct
local-relapse free survival
Time frame: During the study conduct
3-years local relapse free survival
Time frame: During the study conduct
patterns of relapse
Time frame: During the study conduct
acute complications
Time frame: within 8 weeks from starting treatment day
late complications
Time frame: after 8 weeks from starting treatment day
serious complication rate
Time frame: During the study conduct
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Hokkaido University Hospital
North-14 West-5 Kita-ku,Sapporo, Hokkaido, Japan
Sapporo Medical University
S-1,W-16,Chuo-ku,Sapporo, Hokkaido, Japan
Institute of Biomedical Research and Innovation Hospital
Kobe,Chuo-ku,Minatojima-Minamimachi,2-2, Hyōgo, Japan
Kitasato University School of Medicine
Sagamihara,Kitasato,1-15-1, Kanagawa, Japan
Kyoto Universlty Hospital
Kyoto,Sakyoku,Shogoin,Kawahara-cho,54, Kyoto, Japan
Tohoku University Hospital
Sendai,Aoba-ku,Seiryo-machi,1-1, Miyagi, Japan
Tenri Hospital
Tenri,Mishima-cho,200, Nara, Japan
The University of Tokyo Hospital
Bunkyo-ku,Hongo,7-3-1, Tokyo, Japan
...and 6 more locations