Dose Finding Study of Pramipexole (Sifrol) in Patients With Idiopathic Restless Legs Syndrome (RLS)

Inclusion Criteria: 1. Male and female 18-80 years 2. Confident diagnosis of RLS according to International RLS Study Group criteria 3. RLS rating scale for severity score \>15 4. PLM (during time in bed ) index at least 5 per hour 5. Weekly presence of RLS symptoms within last three months 6. Written Informed consent Exclusion Criteria: 1. Women of childbearing potential, who do not use adequate protection such as barrier protection, intrauterine device, or hormonal (oral or subcutaneous) contraception 2. Postmenopausal women less than 6 months after last menses, surgically sterilised, oophorectomised or hysterectomised less than 3 months after operation and not using adequate protection 3. Women neither using adequate protection nor being postmenopausal and their partner is not sterilised at least 6 months post operation or does not use condom 4. Any women not having negative serum pregnancy test at screening