Evaluation of Efficacy of Ophthalmic Solution in Induced Acute Allergic Conjunctivitis

Inclusion Criteria: * history of ocular allergies and a positive skin test reaction to cat hair, * cat dander, grasses, ragweed, and/or trees within the past 24 months; * calculated best-corrected visual acuity of 0.6 logMar or better in each eye; - positive bilateral conjunctival allergy challenge reaction Exclusion Criteria: * narrow angle glaucoma, * clinically significant blepharitis, follicular conjunctivitis, iritis * pterygium or diagnosis of dry eye * ocular surgical intervention within 3 months * history of refractive surgery within 6 months * known history of retinal detachment, diabetic retinopathy, or progressive retinal disease * presence of active ocular infection positive history of an ocular herpetic infection * preauricular lymphadenopath manifest signs or symptoms of clinically active allergic conjunctivitis