Safety of Daily Dose Esomeprazole for GERD for Pediatric and Adolescent Patients

Inclusion Criteria: * Provision of signed written informed consent from the patient's parent/guardian, and assent from the patient prior to conducting of any study-related procedures. * Patients must be male or female between the age of 12 and 17 years, inclusive. * Patients must have a clinical diagnosis of GERD made by the investigator based on any of the following factors: history, physical examination, review of systems, laboratory test results, or information from diagnostic testing. Exclusion Criteria: * Patients who have used a PPI within 14 days prior to randomization, including over-the-counter Prilosec®. * Patients who have used any prescription or over-the-counter treatment for symptoms of gastroesophageal reflux disease (GERD), such as Histamine 2 Receptor Antagonists (H2RA) or prokinetics, within 3 days prior to randomization. Antacids may be used, except for those containing bismuth. * Patients with a known hypersensitivity, allergy, or intolerance to any component of esomeprazole or omeprazole.