Efficacy and Safety of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-06)

Main inclusion criteria: * Patients with chronic obstructive pulmonary disease * Current smoker or ex-smoker * 30 to 80% of predicted FEV1 after inhalation of short acting beta stimulant Main exclusion criteria: * Patients with poorly controlled COPD * Patients who need for long-term oxygen therapy * Patients who have concurrent respiratory diseases such as asthma, diffuse panbronchiolitis, congenital sinobronchial syndrome, bronchiolitis obliterans, bronchiectasis, active tuberculosis, pneumoconiosis, pulmonary lymph vascular myoma, which are considered to affect the evaluation