The purpose of this study is to evaluate whether once daily treatment for up to 8 weeks of calcipotriol plus betamethasone dipropionate gel is more effective than twice daily treatment of calcipotriol scalp solution in patients with scalp psoriasis. The primary outcome is patients with clear or minimal disease after 8 weeks treatment. Further the occurrence of relapse and rebound after end of treatment in patients with clear or minimal disease will be investigated.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
300
Universitair Ziekenhuis Sint Raphaël, Dienst Dermatologie
Leuven, Belgium
Windsor Clinical Research Inc.
Windsor, Ontario, Canada
Department of Dermatology, Marselisborg Centres
Aarhus, Denmark
Hôpital de L'Archet, Service de Dermatologie
Nice, France
Overall disease severity according to investigator's assessment at week 8
Total sign score at week 8
Score for redness, thickness and scaliness at week 8
Overall disease severity according to the investigator's assessment at week 2 and 4
Overall disease severity according to patients at week 8
Relapse and rebound during the study
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Läkarhuset
Gothenburg, Sweden