The purpose of the study is to determine whether castor oil is effective in inducing labor.
Castor oil is traditionally given by midwives in order to induce labor. Its efficacy as an initiator of labor was previously tested only in one clinical trial. Unfortunately this study (by Garry et al.) was not sufficiently controlled. We intent to recruit 84 healthy pregnant women with no contraindication to vaginal delivery that had past their due date. Women will be randomly and blindly divided into equal sized intervention group and control group. Intervention group will be given 60 mL of castor oil in 140 mL of orange juice, while control group will be given a placebo with similar texture. Primary outcome to be tested is the percentage of women entering active labor within 24 hours of administration.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
82
Patients who received castor oil for labor induction
Patients who received sunflower oil as a placebo
Hadassah Medical Organization
Jerusalem, Israel
Delivery within 24 hours of administering castor oil/placebo
Actual time of delivery
Time frame: two weeks
Neonatal apgar scores
Neonatal APGAR scores
Time frame: 1 minute and 5 minute after delivery
Umbilical artery pH and Base Excess
Umbilical artery gases
Time frame: Immediately at birth
Neonatal complications including hospitalization in NICU
Were there any admissions to NICU, what was the reason ?
Time frame: immediately after birth
Mode of delivery (ie. Normal delivery Vs. Cesarean delivery)
Mode of delivery
Time frame: Within two weeks of enrollment
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