Patients with ulcerous colitis and Crohn's disease, age 18-60, with a relapse within the last 18 months and an activity index ≥4, with a long time stress level ≥60 on the perceived stress questionnaire (PSQ) were randomized to a stress management intervention program or treatment as usual and followed up for 18 months.
The study includes distressed patients with ulcerous colitis and Crohn's disease with relapse or enduring activity last 18 months and an simple activity index ≥4, on stable medication last 4 weeks. All patients were followed by a gastroenterologist at baseline, 3, 6, 12 and 18 months follow up and a psychiatrist or clinical psychologist at 18 months. Half of the patients received additional psychosocial intervention (education, relaxation, supportive psychotherapy with stress management). Assessments include gastrointestinal assessments; blood tests; psychiatric evaluations and psychometric evaluations.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
114
3x3 hours group intervention followed by 6-9 hours individual psychotherapy based on cognitive behavioral methods
RRHF
Oslo, Norway
Improvement in activity index.
Time frame: 18 months
Reduction of inflammatory parameters.
Time frame: 18 months
Reduction in number of relapses.
Time frame: 18 months
Quality of life improvement
Time frame: 18 months
Psychobiological factors related to improvement
Time frame: 18 months
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