DBT and Escitalopram in Borderline Personality Disorder

Bronx VA Medical Center

Overview

Subjects will receive six months of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist. Half the subjects will concurrently receive escitalopram while half will receive placebo, in a randomized double-blind design.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Conditions

Borderline Personality Disorder

Interventions

Dialectical Behavioral TherapyBEHAVIORAL

EscitalopramDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: Is a male or female between 18 and 60 who meets criteria for Borderline Personality Disorder and has been off psychotropic medications for at least 2 weeks (6 weeks for fluoxetine). \- Exclusion Criteria: Meets criteria for Schizophrenia, Bipolar Disorder, Mental Retardation, current or recent Substance Dependence or a current Major Depressive Episode. Subjects also should not currently be in individual psychotherapy. (Case management and work therapy programs are allowed.) \-

Locations (1)

Bronx VA Medical Center

The Bronx, New York, United States

RECRUITING

Outcomes

Primary Outcomes

Measures of impulsivity, aggression, affective impulsivity, immediate and delayed memory, and cognitive processing at baseline, 6 months and 9 months

Central Contacts

Emily Hart

CONTACT

212-241-0441 mpgroup@mssm.edu

Data from ClinicalTrials.gov

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