Microvascular Reactivity.

Yale University20 enrolled

Overview

This study attempts to test capillary responses to various challenges without the need for iontophoresis (electrical current).

Studies of microvascular responsiveness often employ iontophoresis to fascilitate drug absorption. Iontophoresis is a confounding stimulus in such studies, and we are attempting to create tests of the microvasculature that do not require iontophoretic drug delivery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diabetes Retinopathy Vascular Pathology

Interventions

Laser Doppler Flowmetry with topical acetylcholine and nitroglycerinDEVICE

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: diabetic. - Exclusion Criteria: not on nitrates or mydriatic eye drops within 48 hours. \-

Locations (1)

Yale School of Medicine

New Haven, Connecticut, United States

Data from ClinicalTrials.gov

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