* To demonstrate that rabies vaccine administered according to the Thai Red Cross, (TRC)-ID regimen (2-2-2-0-1-1) is not inferior to rabies vaccine administered according to the ESSEN IM regimen in terms of Geometric Mean Titers (GMTs) at D28, in subjects with a WHO category III rabies exposure,or, * To demonstrate that Rabies vaccine administered according to the ZAGREB-IM regimen (2-1-1) is not inferior to Rabies vaccine administered according to the ESSEN IM regimen in terms of GMTs at D28, in subjects with a WHO category III rabies exposure. Secondary objectives: 1. To describe the immunogenicity profile of each regimen 2. To assess the safety of the vaccine in each group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
405
0.1 mL, ID (TRC regimen)
0.5 mL, IM (ZAGREB regimen)
0.5 mL, IM (ESSEN regimen)
Unnamed facility
Hyderabad, India
Unnamed facility
Kolkata, India
Unnamed facility
Lucknow, India
Immunogenicity: To provide information concerning the immune response of Purified Verocell Rabies Vaccine
Time frame: 6 months post-vaccination
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