Cortical Reorganisation in Patients With Primary Headache Disorders

Danish Headache Center

Overview

Primary headache disorders are now accepted as physiological diseases, and advanced imaging-techniques have demonstrated a migraine generator in the brain stem and increased stimulus sensitivity in these patients. The underlying neuronal dysfunctions remain to to clarified and the existing neurophysiological methods have not yet been useful. More sensitive and reliable methods are therefore highly needed. The aims of the study are therefore to develop a sensitive and reliable method to demonstrate a cortical reorganisation and expansion of pain sensitive cortical areas in patients with migraine or tension-type headache.

Study Type

OBSERVATIONAL

Conditions

Migraine Without Aura Chronic Tension-Type Headache

Interventions

EEC-techniquesDEVICE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis og migraine without aura or chronic tension-type headache Exclusion Criteria: * serious somatic or psychiatric diseases including depression * overuse of analgesics * regular intake of opiates or benzodiazepines * intake of prophylactic headache medication * pregnancy

Locations (1)

Danish Headache Center; Department of Neurology, Glostrup Hospital, University of Copenhagen

Glostrup, Copenhagen, Denmark

Data from ClinicalTrials.gov

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