Molecular Genetic and Pathological Studies of Anal Tumors

Stanford University7 enrolled

Overview

Study the Genetics of Anal Cancer

To determine the status of previously identified anal cancer molecular markers and any correlations with outcome as well as to discover new molecular biomarkers through correlating molecular data with clinical outcome. Study of tissue samples and cells from biopsies of your lesion and blood sample. We hope to learn the role genes and proteins may play in the development of anal cancer. Experiments will be performed using this tissue and blood, include analysis of DNA, analysis of RNA expression levels, analysis of protein levels of important gene products, and development of tissue culture cell lines.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Rectal Cancer Colon Cancer Colonic Neoplasms Anal Cancer

Interventions

genetic analysisOTHER

standard of care

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria:Inclusion Criteria: * Patients with anal tumors * Undergoing surgery for elective colon and rectal surgery Exclusion Criteria:No other patients other than adult patients with anal cancer or high risk for anal cancer refered to Stanford will be enrolled to the study. No Children will be included to the study

Locations (1)

Stanford University School of Medicine

Stanford, California, United States

Outcomes

Primary Outcomes

Genetic analysis of blood sample as well as tissues , will provide us with any possible tumor marker for a better prognostic indicator.

Time frame: Annual assessment.

Data from ClinicalTrials.gov

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