Study In Patients With Type 2 Diabetes Who Are Taking Metformin And Sulfonylurea, Metformin And Insulin, Or Insulin

Inclusion criteria: * Must have been diagnosed with Type 2 diabetes at least three months prior to screening. * Must be taking either metformin and a sulfonylurea, metformin and insulin, or insulin only, and doses of these medications must have been stable for at least three months. * Must have a Body Mass Index (BMI) of between 24 and 35. * If female, the subject must be post-menopausal. * HbA1c levels must be between 7% and 10%. * Subjects must be eligible for MRI scanning (ie, no metal implants, pacemaker, etc). Exclusion criteria: * Suffer from claustrophobia. * Use of tobacco, nicotine, or illegal drugs of abuse. * Use of caffeine within two days prior to each study visit. * HIV, hepatitis, edema, untreated blood pressure problems, heart, lung, nervous system or kidney disease, history of blood clots in the legs, diabetic neuropathy, or untreated thyroid disease. * Use of drugs or medications that affect the levels of fluid in the body, such as diuretics.