This is a multicenter, randomized, double-blind, placebo-controlled, parallel-design, exploratory study of orally administered ERB-041 in subjects with active IC. The primary objectives of this study will be to investigate ERB-041's activity on levels of urinary APF, explore the gene expression response in peripheral blood mononuclear cells (PBMC), and to evaluate the safety of ERB-041 in women with active IC.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Unnamed facility
Glendora, California, United States
Unnamed facility
Redding, California, United States
Unnamed facility
San Diego, California, United States
Safety
Levels of urinary antiproliferative factor (APF)
Peripheral blood mononuclear cell (PBMC) gene expression profiles
Serum and urinary biomarkers of IC
Clinical Activity:
Global Response Assessment (GRA)
O'Leary-Sant IC Symptom (ICSI) and Problem (ICPI) Index
Pelvic Pain and Urinary/Frequency (PUF) Symptom Scale
Female Sexual Function Index (FSFI)
Voiding Diary
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Unnamed facility
Aventura, Florida, United States
Unnamed facility
Kansas City, Kansas, United States
Unnamed facility
Jackson, Michigan, United States
Unnamed facility
Springfield, Oregon, United States
Unnamed facility
Philadelphia, Pennsylvania, United States
Unnamed facility
Philadelphia, Pennsylvania, United States
Unnamed facility
Philadelphia, Pennsylvania, United States
...and 6 more locations