The purpose of this protocol is to determine the single-dose pharmacokinetics and immunogicity of BMS-188667 administered as a 1 hour intravenous infusion with extended pharmacokinetic sampling. Safety of all subjects will be assessed in a double blind fashion through the inclusion of placebo controls at each dose level.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
32
California Clinical Trials Medical Group
Beverly Hills, California, United States
Pharmacokinetics throughout study period
Time frame: Until Day 43 or Day 120 depending on dose level
Safety and Immunogenicity throughout study period.
Time frame: Until Day 43 or Day 120 depending on dose level and duration of adverse events
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