Preanalgesic Effect of Gabapentin in Total Knee Repair

Texas Health Resources24 enrolled

Overview

The purpose of this study is to determine whether gabapentin, as a one time administration prior to a total knee replacement procedure, has opioid sparing effects and a reduction in pain scores.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Pain

Interventions

GabapentinDRUG

PlacebosDRUG

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing total knee replacement who received pain management by the following modality: * Intravenous patient-controlled analgesia (IV-PCA) opioid * Local femoral nerve block with 1.5% mepivacaine 20 ml and 0.5% ropivacaine 20 ml Exclusion Criteria: * Age \< 18 years old

Locations (1)

Presbyterian Hospital of Dallas

Dallas, Texas, United States

Data from ClinicalTrials.gov

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