A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy

Chinese University of Hong Kong560 enrolled

Overview

* To determine the prevalence of colonic neoplasm in patients who had previously undergone screening colonoscopy * To determine the optimal time interval for re-screening in average risk individuals * To determine potential baseline characteristics that predicts adenoma recurrence

Colorectal cancer (CRC) is the second commonest cancer in Hong Kong, and tends to be increasing. Screening for colorectal cancer can reduce the cancer incidence and mortality by detecting early lesions. However, the best interval for a follow up colonoscopy, particularly for those with normal baseline colonoscopy, remains largely unknown. This study aim to determine the prevalence of colonic neoplasm in average-risk patients who had previously undergone screening colonoscopy and the optimal time interval for re-screening.

Study Type

OBSERVATIONAL

Enrollment

560

Conditions

Colonic Cancer

Interventions

colonoscopyPROCEDURE

proform a follow up colonoscopy in the 5 year period from index colonoscopy

Eligibility

Sex: ALLMin age: 50 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects who are previously participated in one of our two screening colonoscopy studies \[Sung, Gastroenterol 2003; Leung, AJG 2004\] * Asymptomatic on first screening colonoscopy * Age\>50and \<75 * No family history of CRC * No other colonoscopy except the baseline screening colonoscopy Exclusion Criteria: * Subjects who refused consent * Subjects who are not warrant follow up colonoscopy

Locations (1)

Endoscopy Center, Prince of Wales Hospital

Hong Kong (sar), China

Outcomes

Primary Outcomes

The prevalence of advanced colonic adenoma in the re-screening population

Time frame: 5 year from index colonoscopy

Secondary Outcomes

The time to adenoma adenoma development according to different baseline characteristics of patients and colonoscopy findings

Time frame: 5 years from index colonoscopy

Data from ClinicalTrials.gov

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