Efficacy of Adhesive Tablets in Treating Oral Ulcers (Aphthous)

Hadassah Medical Organization50 enrolled

Overview

Recurrent Aphthous Stomatitis (RAS) of the oral mucosa is a common and painful condition. Despite advances in therapeutic means there is still necessary to find a way to alleviate the local pain and discomfort induced by the mucosal ulceration. The hypothesis was to study the effectiveness and acceptance of a herbal adhesive tablets in the treatment of RAS. Participants in the study will be examined for oral lesions, will be instructed how to apply the oral-tablet, and will be interviewed during the follow-up period up to one week after the application.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Ulcer, Aphthous

Interventions

Pro-Pe adhesive tabletDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria (in healthy individuals): * Age above 18 years old. * Non-pregnant women. * Healthy or controlled chronic diseases. * Examination at the Oral Medicine Clinic Inclusion Criteria (in RAS patients): * Age above 18 years old. * Non-pregnant women. * Clinical diagnosis of RAS. * Examination at the Oral Medicine Clinic Exclusion Criteria: * Oral lesion suspected to be malignant. * Ulcerative oral lesion other than RAS. * Another experimental oral intervention within the last 24 hours. * Pregnant women. * Allergy to components of the Pro-pe adhesive tablet

Locations (1)

Hadassah Medical Organization,

Jerusalem, Israel

Outcomes

Primary Outcomes

Serial questionnaires within 1 week post treatment to assess patient's perception, patient's pain relief and local adverse events in comparison to his past experience with other local treatments for oral ulcers.

Data from ClinicalTrials.gov

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