Safety and Feasibility Study of Autologous Bone Marrow Cell Transplantation in Patients With Peripheral Arterial Occlusive Disease (PAOD)

Inclusion Criteria: * Patients with PAOD (Stage III or IV) * Distal arterial occlusions * Patients with Buergers Disease * Signed informed consent Exclusion Criteria: * Successful bypass operation or intervention within the last 3 months * Active infection, feber, chronic inflammatory disease * HIV, Hepatitis * Tumor within the last 5 years, complete remission required * Stroke or myocardial infarction within last 3 months * Renal insufficiency (creatinine \> 2 mg/dl) * Liver disease (GOT \> 2x upper limit oder spontaneous INR \> 1,5). * Anemia (hemoglobin \< \<10 mg/dl) * Thrombocytopenia \< 100.000/µl * Allergies to Aspirin, Clopidogrel, Heparin * Bleeding disorder * Gastrointestinal bleeding within last 3 months * Surgery or trauma within the last 2 months * Pregnancy * Mental retardation * Inclusion in other clinical study within last 30 days