Improvement in Baroreflex Sensitivity in OSAS

Nagoya University

Overview

Individuals with obstructive sleep apnea syndrome (OSAS) are at high risk for cardiovascular morbidity and mortality. The effect of long-term nocturnal therapy with continuous positive airway pressure (CPAP) on daytime baroreflex sensitivity (BRS), a predictor of cardiac death, was investigated in OSAS patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Conditions

Obstructive Sleep Apnea Syndrome

Interventions

continuous positive airway pressure therapyDEVICE

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * obstructive sleep apnea syndrome Exclusion Criteria: * diabetes mellitus, chronic obstructive lung disease, coronary or valvular heart disease, congestive heart failure, renal failure, or endocrine dysfunction. Moreover, none of them were taking b-blockers, vasodilators, or inotropic agents at the time of enrollment in the study.

Locations (1)

Nagoya University of Health Sciences

Nagoya, Japan

RECRUITING

Central Contacts

Akiko Noda, PhD

CONTACT

+81-52-719-1537 a-noda@met.nagoya-u.ac.jp

Data from ClinicalTrials.gov

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