PEEP Test and Gas Exchange in ALI/ARDS Patients

Policlinico Hospital50 enrolled

Overview

The investigators aim to study the effect of different levels of PEEP in ALI/ARDS patients on gas exchange.

In a population of ALI/ARDS patients during mechanical ventilation we will evaluate the effect of different levels of PEEP on gas exchange and dead space.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Acute Respiratory Distress Syndrome

Interventions

Mechanical ventilationPROCEDURE

measurement of gas exchange, dead space, respiratory mechanics 5, 15, 30, 60 minutes from PEEP change (5 and 15 cmH2O)

Eligibility

Sex: ALLMin age: 16 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ALI/ARDS patients requiring mechanical ventilation Exclusion Criteria: * Hemodynamic instability * Barotrauma

Locations (1)

Policlinico Hospital

Milan, Italy

Outcomes

Primary Outcomes

Gas exchange, dead space, respiratory mechanics

Time frame: 5, 15, 30, 60 minutes from PEEP change

Data from ClinicalTrials.gov

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