Early Exposure to Lead and Adult Antisocial Outcomes

National Institute of Environmental Health Sciences (NIEHS)225 enrolled

Overview

Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased risk persists. Outcome measures include official arrest records, diagnoses of Substance Abuse Disorder and Antisocial Personality Disorder, self-report of delinquent behavior, and a psychopathy scale. Predictors include pre-natal and post-natal blood lead levels. Multivariate statistical methods will control for potential confounders/covariates.

Study Type

OBSERVATIONAL

Enrollment

225

Conditions

Lead Poisoning

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: (1) Part of original CLS birth cohort - Exclusion Criteria: (1) Moved out of geographic area \-

Locations (1)

Children's Hospital Medical Center

Cincinnati, Ohio, United States

Outcomes

Primary Outcomes

Lead Exposure and Antisocial Behavior

Time frame: Prenatal (1-2 trimester) and postnatal on a quarterly and bi-annual basis (until 6.5 years)

Data from ClinicalTrials.gov

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