Frontier Registry II Bifurcation Stent System Registry

Inclusion Criteria: * Other lesions in different epicardial vessels must be successfully treated prior to bifurcation procedure. * Native parent vessel suitable to receive at least a 2.5mm x 18mm FRONTIER stent (\>2.5mm and \<4.0mm diameter with a side branch of \>2.0mm) with a lesion length \<15mm determined by visual assessment . * Target main branch vessel must be a major epicardial native vessel. * Appropriate lesion morphology. * Target lesion is restenosis following original treatment by PTCA only (no in-stent restenosis). Exclusion Criteria: * Estimated artery reference diameter \<2.5mm * Patients with diffuse disease defined as long segments of abnormal vessel without interposed areas of normal vessel * Target lesion contains thrombus. * Target lesion is aorto-ostial or left main stem location. * Untreated lesion \>50% diameter stenosis proximal or distal to target lesion after the planned target lesion intervention. * Patients with a contraindication for anti-platelet / anti-coagulation therapy. * Target lesion distal to previously placed stents. * Fibrotic or calcified lesions that cannot be pre-dilated.