Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis

Phase 4CompletedNCT00286351

Rigshospitalet, Denmark20 enrolled

Overview

Does a combination of Arimidex and Zoladex make endometriomas shrink and how is the following IVF outcome

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Endometriosis

Interventions

Combined treatment with Arimidex and Zoladex before IVFDRUG

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Endometrioma(s)with a size of 20-70 mm, persisted for at least 3 cycles * Couples with indication and wish for IVF/ICSI * Age of women: 20-40 years * Regular menstrual cycle within normal range (21-35 days) * Body Mass Index (BMI): 18-30 kg/m2 Exclusion Criteria: * History with osteoporosis, liver-, kidney- or heart disease or thromboembolic disease * Treatment of endometriosis with GnRH agonist during the last 3 month

Locations (1)

The Fertility Clinic, Copenhagen University Hospital, Rigshospitalet

Copenhagen, Copenhagen East, Denmark

Outcomes

Primary Outcomes

size of endometriomas after 2½ month of combined downregulation

Data from ClinicalTrials.gov

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