A Double Blind Randomized Controlled of Placebo and Nebulized Lidocaine for Migraine Headache

Kern Medical Center150 enrolled

Overview

Migraine headaches have previously been shown to be responsive to intranasal lidocaine in a small study. Using a nebulizer to administer the drug would improve the feasibility of using the treatment. It would also spare the patient narcotics with their attendant side effects. Because of the potential for placebo effect a placebo control is necessary in this study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

150

Conditions

Migraine Headache

Interventions

LidocaineDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Meets IHS criteria for migraine Exclusion Criteria: * Pregnant * Breast feeding * Allergic to Lidocaine * Worst or first Headache * Abnormal neurological exam * Substance abuse within 6 months * Cardiac, liver or pulmonary disease * Participation n another study within 30 days

Locations (1)

Kern Medical Center

Bakersfield, California, United States

Outcomes

Primary Outcomes

Resolution of symptoms

Secondary Outcomes

Improvement in 10 point pain score

Data from ClinicalTrials.gov

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