Efficacy and Safety Study of Chromium Picolinate + Biotin on Glucose and Cholesterol Control in T2DM

Inclusion Criteria: 1. Diagnosis of type 2 diabetes \> 12 months. 2. Male and female between the ages of 18 and 70 years, inclusive. 3. HbA1c \> 7.0%. 4. Subject must be receiving an anti-hyperglycemic medication. Medication dosage must be stable for at least 60 days prior to entering trial. Insulin usage must be for rescue purposes only. Rescue insulin use may not be more than once per week. 5. Subjects with a body mass index (BMI) \>/= 25 and \< 35. 6. Subject must be ambulatory. 7. Willing to perform self-administered blood glucose monitoring. 8. Willing to complete all study related requirements. 9. Subject will provide written consent to participate in the trial and this consent must be given voluntarily. Exclusion Criteria: 1. Diagnosis of type 1 diabetes. 2. Hypoglycemic event requiring EMS intervention within 12 months. 3. Diabetic Ketoacidosis (DKA) within 12 months. 4. Subjects taking any supplement containing chromium picolinate within the last 90 days prior to enrollment. 5. Subjects taking a supplement or multivitamin containing any other form of chromium \> 120 mcg/daily within the last 30 days prior to enrollment. 6. Creatinine \> 2.0 x ULN; AST or ALT \> 2.0 x ULN; Total Bilirubin \> 1.5 x ULN 7. COPD, CHF, Angina, HTN, MI, or any other CVD requiring hospitalization within 12 months. 8. History of cerebrovascular accident (CVA), pulmonary embolism (PE), or an unresolved deep vein thrombosis (DVT). 9. History of CABG, PTCA, or any other reperfusion therapy within 12 months. 10. Seated systolic BP \> 160 mmHg. 11. Morbid obesity. 12. Any psychiatric or mental health issue that would prevent the subject from completing the study. (e.g. Severe depression, schizophrenia, high suicide risk, bi-polar disorder, dementia, substance abuse, etc,) 13. History of any serious immunosuppressive disorder or current immunosuppressive therapy. 14. Female subjects who are pregnant or nursing, or are planning on becoming pregnant during the study. 15. Any illness or complication factor that, in the opinion of the investigator, would jeopardize the subject's health or well being by participating in the study or would interfere with the subject successfully completing the study. 16. Current diagnosis of any uncontrolled metabolic disease that would affect carbohydrate or glucose metabolism other than type 2 diabetes. (e.g. hyper or hypothyroidism). (NOTE: Subject's condition must be stable for \> 12 months with no medication changes within the last 12 months preceding enrollment. Subject's TSH must be within range of normality at the time of enrollment to qualify). 17. Current participation in any other clinical research trial for any product or device, or participation in said clinical trials within 30 days prior to enrollment.