Effect of Whole Body Vibration on Bone and Fall Related Parameters

Phase 3TerminatedNCT00292916

University of Erlangen-Nürnberg Medical School150 enrolled

Overview

The effect of whole body vibration (WBV) on bone strength and fall frequency in older adults is still vague. Although there is some evidence that WBV may impact Bone Mineral Density in very frail elderly, there is a lack of data concerning the effect of WBV in community-living elderly woman. We hypothesize that WBV significantly affects bone parameters as assessed by DXA, QCT, US and bone markers with parallel positive changes of fall related risk factors (power, strength, balance, and reaction time). We further hypothesize that the effects of WBV were superior to conventional resistance exercise.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

150

Conditions

Atrophy

Interventions

whole body vibration

Eligibility

Sex: FEMALEMin age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * community living elderly females \>/=65 years * live expectation \> 2 years Exclusion Criteria: * secondary osteoporosis * CVD-events including stroke * participation in other studies * medication and illness affecting bone metabolism within the last 2 years * medication with impact on falls * low physical performance (\<50 Watt during ergometry) * excessive alcohol-intake

Outcomes

Primary Outcomes

BMD after 6, 12 and 18 months

strength

power

Secondary Outcomes

balance

bone markers