Evaluation of Two Different Non-invasive Techniques to Monitor the Clearance of Actinic Keratosis Lesions

Inclusion Criteria: * At least 5 clinically typical, visible, discrete, nonhyperkeratotic, nonhypertrophic AK lesions * Free of any significant findings (e.g tattoos) in the potential application site area. * Willing to discontinue sun-tanning and use of sunbed/sun parlour use * Willing to stop use of moisturisers, body oils, and over the counter retinol products or products containing alpha or beta hydroxyacids in the treatment or surrounding area. * Willing ot withhold sunscreen and/or moisturiser use for 24 hours prior to each clinical assessment Exclusion Criteria: * Evidence of unstable or uncontrolled clinically significant medical condition. * Any dermatological disease and or condition in the treatment of the surrounding area that may be exacerbated by treatment with imiquimod. * Currently participating in another clinical study or have completed another study within an investigational drug within the past 30 days. * Have active chemical dependency or alcoholism * Have know allergies to any excipient or study cream * Have received previous treatment with imiquimod for any indication within the treatment area. * Known to be affected by porphyria