Comparing Efficacy and Safety of Tacrolimus With Steroids or Monoclonal Anti-IL2R Antibody in Hepatitis C Virus (HCV) Positive Liver Transplant Patients

Inclusion Criteria: * Patients 18 to 65 years of age who will undergo primary orthotopic liver or split liver allograft transplantation for HCV-cirrhosis are eligible for the study. * Patients receiving a cadaveric liver transplant with compatible ABO blood type can be included. Exclusion Criteria: * Recipient of multi-organ transplant * Recipient of an auxiliary graft * Patient is receiving ABO incompatible graft * Patients requiring immunosuppressive treatment * Patients requiring ongoing corticosteroid therapy. * Patient has significant, uncontrolled concomitant infections and/or severe diarrhoea, vomiting, active upper gastro-intestinal tract malabsorption or active peptic ulcer. * Patient or donor is known to be HIV positive. * Patient is allergic or intolerant to study medication * Patient is pregnant or breast-feeding. * Patient has been previously enrolled in this study