Effect of Sildenafil on Endothelial Function

Rambam Health Care Campus60 enrolled

Overview

We are investigating the chronic effect of daily assumption of Viagra on the blood vessels function in patients with impotence. The study will include 2 groups: 1- patients with multiple risk factors, e.g. hypertension 2- patients with no cardiovascular risk factors

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

ECT

Masking

DOUBLE

Enrollment

Conditions

Impotence

Interventions

ViagraDRUG

Eligibility

Sex: MALEMin age: 40 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age 40-70 * impotence * with and without hypertension, Hypercholesteremia or DM Exclusion Criteria: * CHF: NYHA \> II * Stable angina: CCS \> II * Nitrate treatment

Locations (1)

Rambam Medical Center, Recanati Autonomic Dysfunction CTR

Haifa, Israel

RECRUITING

Outcomes

Primary Outcomes

Improvement of endothelial function following Viagra treatment, according to platismographia.

Central Contacts

Giris Jacob, Prof., MD, DSc

CONTACT

972-4-854-2467 g_jacob@rambam.health.gov.il

Yuram Vardi, Prof., MD

CONTACT

972-4-854-2819 y_vardi@rambam.health.gov.il

Data from ClinicalTrials.gov

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