Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

Vilnius University60 enrolled

Overview

The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Opiate Dependence

Interventions

KetamineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed opiate dependence according to ICD 10 and/or DSM 4; * Duration of substance abuse more than 1 year * No or minor co-morbidities; * Grade I-II according to physical status classification system of American Society of Anesthesiologists. Exclusion Criteria: * Current history of long acting opiate or poly-substance abuse; * Acute medical or surgical condition; * Pregnancy; * Breastfeeding.

Locations (1)

Vilnius University Emergency Hospital

Vilnius, Lithuania

Data from ClinicalTrials.gov

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