Randomized controlled clinical trial of periocular corticosteroids as adjunctive therapy to photodynamic therapy (PDT) for patients with neovascular age-related macular degeneration (AMD). Patients undergoing PDT are randomized to either a periocular corticosteroid injection with 40 mg of triamcinolone acetonide or observation just prior to PDT. Patients are followed for 6 months. Primary outcome is leakage from choroidal neovascularization (CNV) at 3 months on fluorescein angiography.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Johns Hopkins Univeristy School of Medicine
Baltimore, Maryland, United States
Oregon Health Science Univeristy
Portland, Oregon, United States
Fluorescein leakage from choroidal neovascularization on fluorescein angiography at 3 months after randomization.
Safety
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