Implantation of bone marrow cells, including endothelial progenitor cells, into ischemic limbs has been shown to improve collateral vessel formation. In the present study the safety and feasibility of autologous blood mononuclear cells implantation will be investigated in patients with severe peripheral atherosclerosis.Twenty cases will be enrolled. Improvement in the ankle-brachial pressure index (ABI:\>0.1), ischemic ulcers and angiography as well as laser doppler flow will be evaluated until six months.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
20
University of Naples
Naples, Italy
RECRUITINGClinical and instrumental indexes of functional impairment of peripheral atherosclerosis.
Angiographic and laser doppler measurements after six months from treatment.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.