An Efficacy and Tolerability Study for Topiramate in Obese Patients With Binge Eating Disorder.

Inclusion Criteria: * Have been meeting the diagnostic criteria for binge eating disorder (according to the Diagnostic and Statistical Manual for Mental Disorders - IV Edition criteria) with at least 2 days of binge eating per week and severity at least moderate defined by binge eating scale (score = 17) * BMI = \> 30 kg/m2 to \< 46 kg/m2 * Women must be post menopausal for at least one year or surgically sterilized (hysterectomy, tubal ligation), or practice sexual abstinence or use an acceptable method of birth control (i.e. a hormonal contraceptive, spermicide plus barrier method, intrauterine device and/or vasectomized partner) Exclusion Criteria: * Has a history or actual diagnostic of significant psychiatric disorder (schizophrenia, psychosis, major affective disorder, suicide risk, dementia, abuses alcohol or other drugs) * has a malignancy or a history of malignancy within the past 5 years (except basal cell carcinoma) * evidence of uncontrolled thyroid disorders * uncontrolled hypertension (defined as a diastolic blood pressure \>110 mm/Hg and/or a systolic blood pressure \>180 mm/Hg with or without medication). Hypertensive patients on medications must have been on the same dose of the same antihypertensive medication for at least two months * history or significant renal failure or glaucoma.