The Effect of CoQ10 Administration on Hemodialysis Patients

University of Shizuoka40 enrolled

Overview

The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.

Oxidative stress has been recognized as a potential risk factor for such complications as atherosclerosis in hemodialysis patients. This study investigates whether CoQ10 administration is effective for protecting oxidative stress in hemodialysis patients. The subjects were recruited from day-time hemodialysis patients in Iwata City Hospital. 100 mg CoQ10 was administered every HD for 6 months. Several oxidative and antioxidative markers were measured in plasma at pre, 1, 3, 6 months and after washout.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Chronic Renal Failure Hemodialysis

Interventions

Coenzyme Q10 (drug)DRUG

Eligibility

Sex: ALLMin age: 0 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * hemodialysis for at least 6 months Exclusion Criteria: * none

Locations (1)

Iwata City Hospital

Iwata, Shizuoka, Japan

Outcomes

Primary Outcomes

Oxidative protein concentration at 6 month

Antioxidant capacity at 6 month

Data from ClinicalTrials.gov

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